Amanda Lewis, Ph.D.

 Bacteria, Glycobiology, and Women's Health


Department of Ob/Gyn and Reproductive Sciences

Division of Maternal-Fetal Medicine


Glycobiology Research and Training Center

University of California San Diego

Contact me: e-mail: a1lewis[at]

The Vaginal Microbiome

The composition of bacteria in the human vagina has been linked to health and disease. Our lab builds experimental models to understand how vaginal bacteria interact with each other and the host and how these events lead to colonization and pathophysiology.

Gardnerella vaginalis

Gardnerella is one of the most abundant bacteria in the vagina during a condition known as bacterial vaginosis (BV).

In multiple mouse models, of co-inoculation, we show that Gardnerella supports colonization by other bacteria and triggers other pathogens to exhibit more virulent characteristics.

Sialic acids in biology
and  disease

Sialic acids and related carbohydrates are rich at mucosal surfaces and are involved in many host-microbe interactions. We investigate processes in sialic acid evolution,  biology, and disease, with an emphasis on infection and the microbiome.