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Dept of Ob/Gyn and Reproductive Sciences
Glycobiology Research and Training Center
UC San Diego
Gardnerella vaginalis
generates features of bacterial vaginosis in a mouse model
BV-like phenotypes of the model include:
2) mucus degradation (higher free & lower total sialic acid) {JBC13} (Fig XB-C);
3) epithelial exfoliation response (# epithelial cells in vaginal specimens) (Fig XD);
4) ‘clue-like’ cells in vaginal washes; and
5) bacterial-epithelial interaction in H&E-stained vaginal tissue sections (Fig XE).
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